Luminescent organoplatinum(II) complexes containing bis(N-heterocyclic carbene) ligands selectively target the endoplasmic reticulum and induce potent photo-toxicity

Chem. Commun., 2013, 49,5423-5425
DOI: 10.1039/C3CC40953H, Communication

Taotao Zou, Chun-Nam Lok, Yi Man Eva Fung, Chi-Ming Che
Luminescent platinum(II) complexes (such as 1) can highly selectively localize to the endoplasmic reticulum (ER) domain, and induce ER stress and cell apoptosis. Some of them show potent photo-toxicity to cancer cells.
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