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Chem. Commun., 2025, Advance Article
DOI: 10.1039/D5CC00348B, Communication
DOI: 10.1039/D5CC00348B, Communication
Dhrubajyoti Datta, Jayanta Kundu, Patrick Miller, Mehreen S. Khan, Juan Salinas, June Qin, Sarah LeBlanc, Tuyen Nguyen, Haiyan Peng, Christopher S. Theile, Martin Egli, Muthiah Manoharan
Both E- and Z- isomers of 6′-vinylphosphonate work as stable phosphate mimic at the 5′ end of the antisense strand and work as efficiently as 5′-(E)-vinylphosphonate in vitro and in vivo.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Both E- and Z- isomers of 6′-vinylphosphonate work as stable phosphate mimic at the 5′ end of the antisense strand and work as efficiently as 5′-(E)-vinylphosphonate in vitro and in vivo.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
