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Synthesis and in vitro evaluation of a multifunctional and surface-switchable nanoemulsion platform

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Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC43618G, Communication
Anita Gianella, Aneta Joanna Czajkowska , Freek Hoeben, Henk Janssen, Peter Jarzyna, David Cormode, Kevin D. Costa, Satish Rao, Omid Farkhzad, Robert S Langer, Zahi Fayad, Willem Mulder
We present a multifunctional nanoparticle platform that has targeting moieties shielded by a matrix metalloproteinase-2 (MMP2) cleavable PEG coating. Upon incubation with MMP2 this surface-switchable coating is removed and the...
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