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Zinc finger peptide cleavage by a dinuclear platinum compound

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Chem. Commun., 2013, 49,6986-6988
DOI: 10.1039/C3CC44219E, Communication
John B. Mangrum, Ibrahim Zgani, Samantha D. Tsotsoros, Yun Qu, Nicholas P. Farrell
The platinum-assisted cleavage of the C-terminal HIV NCp7 zinc finger is a novel strategy to inactivate this important biological target.
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