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N-Terminal [small alpha]-Amino Group Modification of Peptides by an Oxime Formation/Exchange Reaction Sequence

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Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC42261E, Communication
Man Kin Wong, Karen Ka-Yan Kung, Kong-Fan Wong, King-Chi Leung
A site-specific and efficient method for N-terminal modification of peptides by using oxone for selective oxidation of N-terminal [small alpha]-amino groups of peptides to oximes, followed by transoximation with O-substituted hydroxylamines...
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