Selective [small alpha]-Amination and [small alpha]-Acylation of Esters and Amides via Dual Reactivity of O-Acylhydroxylamines toward Zinc Enolates

Chem. Commun., 2014, Accepted Manuscript
DOI: 10.1039/C3CC49296F, Communication

Qiu Wang, Stacey L. McDonald
Selective [small alpha]-amination and [small alpha]-acylation of esters and amides have been developed; employing O-acylhydroxylamines as a dually reactive aminating and acylating reagent. Treatment of zinc enolates with O-acylhydroxylamines provides solely 1,3-...
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