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A tandem Friedel-Crafts based method for the construction of tricyclic pyrroloquinoline skeleton and its application to the synthesis of ammosamide B

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Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC42463D, Communication
Yohei Takayama, Tatsuya Yamada, Shinya Tatekabe, Kazuo Nagasawa
A total synthesis of ammosamide B (2), a member of pyrroloquinoline alkaloid family isolated from marine Streptomyces, is described. The characteristic core tricyclic structure of 2 was constructed by using...
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