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Synthesis of (spiro)cyclopentapyridinones via Csp3-H functionalization: A post-Ugi gold-catalyzed regioselective tandem cyclization

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Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC43418D, Communication
Dipak D Vachhani, Marzia Galli, Jeroen Jacobs, Luc Van Meervelt, Erik V�lery Van der Eycken
A gold-catalyzed regioselective tandem cyclization of N-propynylbutynamide via Csp3-H functionalization has been described, providing a distinctive methodology for the architecture of cyclopentapyridinones as well as spirocyclopenta-pyridinones.
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