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A highly sensitive immunoassay using antibody-conjugated spherical mesoporous silica with immobilized enzymes

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Chem. Commun., 2014, Advance Article
DOI: 10.1039/C3CC48044E, Communication
Ji Young Eum, Sang Youn Hwang, Youngjun Ju, Jong Min Shim, Yunxian Piao, Jinwoo Lee, Hak-Sung Kim, Jungbae Kim
A highly sensitive immunoassay was developed by using antibody-conjugated spherical mesoporous silica with immobilized enzymes. High ratio of enzyme to antibody improved both the sensitivity and dynamic range.
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