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H2O2-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin

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Chem. Commun., 2014, Advance Article
DOI: 10.1039/C3CC48108E, Communication
Yasunori Okamoto, Akira Onoda, Hiroshi Sugimoto, Yu Takano, Shun Hirota, Donald M. Kurtz, Yoshitsugu Shiro, Takashi Hayashi
The O2-binding carboxylate-bridged diiron site in DcrH-Hr with an engineered His residue in place of Ile119 promotes the oxidation of guaiacol and 1,4-cyclohexadiene upon addition of H2O2.
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