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Enantioselective synthesis of diaryl aziridines using tetrahydrothiophene-based chiral sulfides as organocatalysts

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Chem. Commun., 2014, 50,1101-1103
DOI: 10.1039/C3CC47550F, Communication
Meng-Ting Huang, Hsin-Yi Wu, Rong-Jie Chein
This work describes catalytic and asymmetric aziridinations (15 examples, 95-98% ee) of benzyl bromide and imines via the imino Corey-Chaykovsky reaction using (thiolan-2-yl)diarylmethanol benzyl ether as an organocatalyst.
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