Chem. Commun., 2014, 50,994-996
DOI: 10.1039/C3CC47800A, Communication
DOI: 10.1039/C3CC47800A, Communication
Jianfeng Zheng, Lili Lin, Yulong Kuang, Jiannan Zhao, Xiaohua Liu, Xiaoming Feng
The first catalytic asymmetric hetero-Diels-Alder reaction of Brassard's dienes with isatins was realized using Mg(II)/N,N[prime or minute]-dioxide complexes as catalysts, affording the corresponding chiral spirolactones bearing tetrasubstituted centers in up to 99% yield with up to 99% ee and >99 : 1 dr within 3 hours.
The content of this RSS Feed (c) The Royal Society of Chemistry
The first catalytic asymmetric hetero-Diels-Alder reaction of Brassard's dienes with isatins was realized using Mg(II)/N,N[prime or minute]-dioxide complexes as catalysts, affording the corresponding chiral spirolactones bearing tetrasubstituted centers in up to 99% yield with up to 99% ee and >99 : 1 dr within 3 hours.
The content of this RSS Feed (c) The Royal Society of Chemistry