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Discovery of new G-quadruplex binding chemotypes

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Chem. Commun., 2014, 50,960-963
DOI: 10.1039/C3CC48616H, Communication
Stephan A. Ohnmacht, Ehsan Varavipour, Rupesh Nanjunda, Ingrida Pazitna, Gloria Di Vita, Mekala Gunaratnam, Arvind Kumar, Mohamed A. Ismail, David W. Boykin, W. David Wilson, Stephen Neidle
We report a novel furan-based low molecular weight chemotype with high G-quadruplex affinity and potent anti-proliferative activity.
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