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Construction of DNA-polymer hybrids using intercalation interactions

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Chem. Commun., 2014, Advance Article
DOI: 10.1039/C3CC48726A, Communication
Thomas R. Wilks, Anais Pitto-Barry, Nigel Kirby, Eugen Stulz, Rachel K. O'Reilly
Reversible addition-fragmentation chain transfer (RAFT) polymerisation was used to produce a range of polymers terminated with an acridine group, which intercalates efficiently into dsDNA; the structure of the polymer determines the nature and strength of the interaction.
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