Zinc-mediated addition of diethyl bromomalonate to alkynes for the cascade reaction towards polysubstituted pyranones and tetracarbonyl derivatives

Chem. Commun., 2014, 50,542-544
DOI: 10.1039/C3CC46788K, Communication

Anne Miersch, Klaus Harms, Gerhard Hilt
A sequential three-component one-pot reaction of terminal alkynes, bromomalonate and various acid chlorides mediated by zinc powder led to the formation of pyran-2-ones in good overall yields.
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