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Highly Enantioselective Hydrogenation of 2-Substituted-2-Alkenols Catalysed by ChenPhos-Rh Complex

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Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC47727D, Communication
Weiping Chen, Quanjun Wang, Xueying Liu, Bin Li, Huifang Nie
Highly enantioselective hydrogenation of a variety of 2-substituted-2-alkenols has been achieved using ChenPhos-Rh complex as catalyst, giving [greater-than-or-equal]99% ee for most of substrates. Optically active antifungal agent amorolfine was first...
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