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A rapid screen for molecules that form duplex to duplex crosslinks in DNA

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Chem. Commun., 2013, 49,9113-9115
DOI: 10.1039/C3CC45600E, Communication
Maria J. Marin, Benjamin D. Rackham, Andrew N. Round, Lesley A. Howell, David A. Russell, Mark Searcey
A gold-nanoparticle based assay can rapidly determine the crosslinking of DNA duplexes by compounds targeting highly compacted DNA as found in the nucleosome.
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