Sensitive label-free monitoring of protein kinase activity and inhibition using ferric ions coordinated to phosphorylated sites as electrocatalysts

Chem. Commun., 2013, 49,8788-8790
DOI: 10.1039/C3CC43290D, Communication

Min Wang, Gui-Xia Wang, Fang-Nan Xiao, Yun Zhao, Kang Wang, Xing-Hua Xia
Ferric ions show high affinity to the kinase-generated phosphorylated sites of peptides, which allows them as effective electrocatalysts for monitoring of protein kinase activity and inhibition.
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