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Receptor conformational change induces fluoride binding despite competitive water binding

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Chem. Commun., 2013, Advance Article
DOI: 10.1039/C3CC43019G, Communication
Laurent Trembleau, Tim A. D. Smith, Mostafa H. Abdelrahman
Fluoride binding by artificial receptors in pure water is a challenging task due to the high hydration enthalpy of this anion. We show that a water-soluble boron-based tripodal receptor, featuring three flexible ammonium-containing arms, is capable of binding fluoride despite the presence of excess water.
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