A highly cytotoxic modified paullone bearing a TEMPO free-radical unit and its copper(II) complex as potential hR2 RNR inhibitors

Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC45743E, Communication

Anatolie Dobrov, Simone Goeschl, Michael Jakupec, Ana Popovic-Bijelic, Astrid Graslund, P. Rapta, Vladimir Arion
A new paullone-TEMPO conjugate and its copper(II) complex inhibit RNR activity and show high antiproliferative activity in human cancer cell lines.
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