Highly regioselective synthesis of 2,4,5-(hetero)aryl substituted oxazoles by intermolecular [3+2]-cycloaddition of unsymmetrical internal alkynes

Chem. Commun., 2013, 49,8617-8619
DOI: 10.1039/C3CC45410J, Communication

Elli Chatzopoulou, Paul W. Davies
Remote activation of unsymmetrical internal alkynes by nitrogen enables a highly regioselective and convergent gold catalysed synthesis of trisubstituted oxazoles.
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