Chem. Commun., 2013, Advance Article
DOI: 10.1039/C3CC44621B, Communication
DOI: 10.1039/C3CC44621B, Communication
Alice Ghidini, Charlotte Ander, Anna Winqvist, Roger Stromberg
A 3[prime or minute]-methylenephosphonate modified diribonucleotide is highly resistant to phosphodiesterase degradation and most remarkably it is highly resistant towards the action of RNase A, despite the fact that both the vicinal 2[prime or minute]-hydroxy nucleophile and the 5[prime or minute]-oxyanion leaving group are intact.
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A 3[prime or minute]-methylenephosphonate modified diribonucleotide is highly resistant to phosphodiesterase degradation and most remarkably it is highly resistant towards the action of RNase A, despite the fact that both the vicinal 2[prime or minute]-hydroxy nucleophile and the 5[prime or minute]-oxyanion leaving group are intact.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry