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Light-inducible activation of target mRNA translation in mammalian cells

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Chem. Commun., 2013, 49,8338-8340
DOI: 10.1039/C3CC44866E, Communication
Jicong Cao, Manish Arha, Chaitanya Sudrik, Lukasz J. Bugaj, David V. Schaffer, Ravi S. Kane
We have developed a light-inducible translational activation system in mammalian cells based on the light-sensitive reconstitution of an RNA binding domain and a translation initiation domain.
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