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Enhanced Raman Signals from Switchable Nanoparticle Probes

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Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC44781B, Communication
Phyllis Xu, Ju Hun Lee, Ke Ma, Chulmin Choi, Sungho Jin, Joseph Wang, Jennifer N Cha
Signals generated from Surface-Enhanced Raman Spectroscopy (SERS) show large enhancements when a molecule is in the gap between two metal nanoparticles in close proximity. We demonstrate here a DNA-based conformationally switchable nanodumbell structure that modulates the interparticle distance between two gold-silver core-shell nanoparticles to induce significant changes in SERS signal.
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