Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC45002C, Communication
DOI: 10.1039/C3CC45002C, Communication
Zhenlei Song, Gao Lu, Lu Ji, Lin Xinglong, Xu Yongjin, Yin Zhiping
An unusual [1,5]-Brook rearrangement of the lithium alkoxide of geminal bis(silyl) homoallylic alcohol is described. The unique steric and electronic effects of geminal bis(silane) were found to be crucial for promoting this long-range silyl migration, as well as for facilitating the subsequent [gamma]/Z-selective addition of silyl allyllithium with carbonyl compounds to synthesize diverse configurationally defined Z-vinylsilanes.
The content of this RSS Feed (c) The Royal Society of Chemistry
An unusual [1,5]-Brook rearrangement of the lithium alkoxide of geminal bis(silyl) homoallylic alcohol is described. The unique steric and electronic effects of geminal bis(silane) were found to be crucial for promoting this long-range silyl migration, as well as for facilitating the subsequent [gamma]/Z-selective addition of silyl allyllithium with carbonyl compounds to synthesize diverse configurationally defined Z-vinylsilanes.
The content of this RSS Feed (c) The Royal Society of Chemistry