Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC45139A, Communication
DOI: 10.1039/C3CC45139A, Communication
Qi-Lin Wang, Lin Peng, Fei-Ying Wang, Ming-Liang Zhang, Li-Na Jia, Fang Tian, Xiaoying Xu, Li-xin Wang
The first organocatalytic asymmetric sequential allylic alkylation/cyclization of Morita-Baylis-Hillman carbonates and 3-hydroxyoxindoles has been developed to afford spirooxindoles bearing alfa-methylene-gama-butyrolactone motifs in 25-96% yield, 60-94% ee and 54:46->20:1 diastereoselectivity.
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The first organocatalytic asymmetric sequential allylic alkylation/cyclization of Morita-Baylis-Hillman carbonates and 3-hydroxyoxindoles has been developed to afford spirooxindoles bearing alfa-methylene-gama-butyrolactone motifs in 25-96% yield, 60-94% ee and 54:46->20:1 diastereoselectivity.
The content of this RSS Feed (c) The Royal Society of Chemistry