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Thiolated 2-Methacryloyloxyethyl Phosphorylcholine for Antifouling Biosensor Platform

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Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC44357D, Communication
Tatsuro Goda, Miyuki Tabata, Mai Sanjoh, Mai Uchimura, Yasuhiko Iwasaki, Yuji Miyahara
We developed a new building block for protein- and cell- repellant self-assembled monolayer (SAM) from 2-methacryloyloxyethyl phosphorylcholine (MPC) via simple Michael-type addition to one mercapto group in alkanedithiol. The thiolated MPC can offer to functionalize a noble metal electrode to minimize noise signal in biosensing.
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