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Exploiting dense shell/packing principles to invoke stereoselectivity in a reaction accelerated by a chiral dendrimer.

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Chem. Commun., 2013, Accepted Manuscript
DOI: 10.1039/C3CC43830A, Communication
Lance James Twyman, Adam Ellis, Melanie Wallace
As dendrimers approach their dense shell or dense packed limit, a certain amount of conformational organization exists. Any substrate binding within the dendrimer's external layer will experience the same organizational effects. This paper describes how these effects can be exploited towards stereocontrol with respect to binding and reactivity.
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