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Morpholino-decorated long circulating polymeric micelles with the function of surface charge transition triggered by pH changes

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Chem. Commun., 2013, 49,7286-7288
DOI: 10.1039/C3CC43334J, Communication
Yan Zhang, Chenhong Wang, Chuang Xu, Cuiping Yang, Zhenqing Zhang, Husheng Yan, Keliang Liu
Micelles are stealthy at blood and normal tissue pH (7.4) and are internalized into cancer cells at tumor pH (<7) due to the unprotonated/protonated surface morpholino groups.
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