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Palladium-catalyzed regio- and chemoselective ortho-benzylation of C-H bond using a functionalizable primary amide directing group: a concise synthesis of dibenzo[b,e]azepin-6-ones

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Chem. Commun., 2013, Advance Article
DOI: 10.1039/C3CC43835J, Communication
Joydev K. Laha, Pooja U. Shah, Krupal P. Jethava
A palladium-catalyzed regio- and chemoselective direct ortho-benzylation of primary benzamides furnishes substituted diarylmethanes, which upon intramolecular cyclization gives dibenzoazepinones.
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